Set in Toronto, Canada in the late 19th century, Murdoch Mysteries is based on the best-selling novels by crime writer Maureen Jennings and follows the adventures of Detective William Murdoch (Yannick Bisson) who uses innovative inventions and pioneering forensic techniques to crack cases.
Murdoch is aided by the eager but inexperienced Constable George Crabtree (Jonny Harris), sceptical but supportive boss Inspector Brackenreid (Thomas Craig) and accomplished pathologist and Chief Coroner at City Morgue, Dr Julia Ogden (Hélène Joy), Murdoch's staunchest supporter and soulmate.
The third series opens with Murdoch marooned in Bristol, England with no idea who he is or how he got there. To add to the mystery, he's being ruthlessly hunted down by armed men who claim he is a killer. Luckily, he has a friend in local publican Anna Fulford (Lisa Faulkner) and, with her help, he must piece together this very personal and perplexing puzzle.
Later in the series, Murdoch investigates when a priceless Rembrandt vanishes into thin air whilst under heavy guard, looks into a suspicious death at a manor house which is being blamed on an ancient curse and reopens an old case when a convicted murderer miraculously survives his hanging and escapes from the morgue.
Station House Four is also rocked by the kidnapping of Inspector Brackenreid's young son, Bobby, who is snatched whilst playing in the park. To make matters worse, it soon becomes obvious that he was mistaken for the son of a rich business man and that the kidnappers don't realise their error.
This series also introduces the character of James Pendrick (Peter Stebbings), a wealthy philanthropist and inventor and someone who Murdoch should admire... except he has a sneaking suspicion that Pendrick is actually a criminal mastermind!